Syllabus
Course Description
- I. Introduction: top challenges in Bioinformatics
- II. Bio-molecular structures
- Nucleic acids
- Proteins
- III. Comparing sequences and structures
- Sequence alignment
- Structure alignment
- IV. Protein Structure databases
- Protein domains
- Protein structure classification
- V. Stability of bio-molecules
- Semi-empirical energy functions
- Statistical potentials
- VI. Protein structure prediction
- Comparative modeling
- Ab initio prediction
- VII. Bio-molecular simulations
- VIII. Drug design
- IX. Databases and web services